伟德体育在线

MAPK signaling pathway

MAPK信号通路是真核细胞介导细胞外信号到细胞内反应的重要信号转导系统。MAPK通路相关信号是一类高度保守的伟德体育在线激酶家族,共发现有19种MAPKKK(也称MAP3K或MEKK),7种MAPKK(MAP2K)和14种MAPK。它们之间为上、中、下三层级联信号分子,MAPKKK活化MAPKK,后者再活化MAPK,即细胞外信号→MAPK激酶的激酶(MKKK)→MAPK激酶(MKK)→MAPK,调节细胞的生长、分化、凋亡和死亡等多种生理过程。如下图所示,MAPK信号通路主要包含经典MAPK信号通路、JNK/p38MAPK信号通路和ERK5三条信号通路,其中,最早发现的经典的 Ras-Raf-MAPK 信号转导途径,参与各种生长因子、细胞因子、丝裂原以及激素受体活化后的信号转导,在细胞的增殖、生长和分化等方面有重要的调节作用。

Target Antibody Protein Clone 伟德体育投注 Kit
AKT1 AKT1 Antibody AKT1 Protein AKT1 cDNA AKT1 伟德体育投注 Kit
AKT2 AKT2 Antibody AKT2 Protein AKT2 cDNA AKT2 伟德体育投注 Kit
AKT3 AKT3 Antibody AKT3 Protein AKT3 cDNA AKT3 伟德体育投注 Kit
ANGPT1 ANGPT1 Antibody ANGPT1 Protein ANGPT1 cDNA ANGPT1 伟德体育投注 Kit
ANGPT2 ANGPT2 Antibody ANGPT2 Protein ANGPT2 cDNA ANGPT2 伟德体育投注 Kit
ANGPT4 ANGPT4 Antibody ANGPT4 Protein ANGPT4 cDNA ANGPT4 伟德体育投注 Kit
ARAF ARAF Antibody ARAF Protein ARAF cDNA ARAF 伟德体育投注 Kit
AREG AREG Antibody AREG Protein AREG cDNA AREG 伟德体育投注 Kit
ARRB1 ARRB1 Antibody ARRB1 Protein ARRB1 cDNA ARRB1 伟德体育投注 Kit
ARRB2 ARRB2 Antibody ARRB2 Protein ARRB2 cDNA ARRB2 伟德体育投注 Kit
ATF2 ATF2 Antibody ATF2 Protein ATF2 cDNA ATF2 伟德体育投注 Kit
ATF4 ATF4 Antibody ATF4 Protein ATF4 cDNA ATF4 伟德体育投注 Kit
BDNF BDNF Antibody BDNF Protein BDNF cDNA BDNF 伟德体育投注 Kit
BRAF BRAF Antibody BRAF Protein BRAF cDNA BRAF 伟德体育投注 Kit
CACNA1A CACNA1A Antibody CACNA1A Protein CACNA1A cDNA CACNA1A 伟德体育投注 Kit
CACNA1B CACNA1B Antibody CACNA1B Protein CACNA1B cDNA CACNA1B 伟德体育投注 Kit
CACNA1C CACNA1C Antibody CACNA1C Protein CACNA1C cDNA CACNA1C 伟德体育投注 Kit
CACNA1D CACNA1D Antibody CACNA1D Protein CACNA1D cDNA CACNA1D 伟德体育投注 Kit
CACNA1E CACNA1E Antibody CACNA1E Protein CACNA1E cDNA CACNA1E 伟德体育投注 Kit
CACNA1F CACNA1F Antibody CACNA1F Protein CACNA1F cDNA CACNA1F 伟德体育投注 Kit