伟德体育在线

Wnt signaling pathway

伟德体育在线Wnt信号通路是一个复杂的伟德体育在线质作用网络,其功能最常见于胚胎发育和癌症,但也参与成年动物的正常生理过程。如下图所示,现在已发现三种Wnt信号通路,分别是经典Wnt通路(canonical Wnt pathway)、非经典Wnt/平面细胞极化通路(noncanonical Wnt/planar cell polarity pathway,PCP)和非经典Wnt/钙离子通路(noncanonical Wnt/calcium pathway)。所有这三种Wnt信号通路都由Wnt伟德体育在线配体与其受体卷曲受体的结合来激活,将信号传给胞内的散乱伟德体育在线。经典Wnt信号通路参与基因表达的调控,非经典平面细胞极化通路调控细胞骨架控制细胞形状,非经典Wnt/钙离子通路调控细胞内钙离子的浓度。Wnt信号通路常用于临近的细胞之间的通信(旁分泌)或同个细胞自身的通信(自分泌)。Wnt信号通路在动物中高度保守,从果蝇到人类都非常类似。

Target Antibody Protein Clone 伟德体育投注 Kit
APC APC Antibody APC Protein APC cDNA APC 伟德体育投注 Kit
APC2 APC2 Antibody APC2 Protein APC2 cDNA APC2 伟德体育投注 Kit
AXIN1 AXIN1 Antibody AXIN1 Protein AXIN1 cDNA AXIN1 伟德体育投注 Kit
AXIN2 AXIN2 Antibody AXIN2 Protein AXIN2 cDNA AXIN2 伟德体育投注 Kit
BAMBI BAMBI Antibody BAMBI Protein BAMBI cDNA BAMBI 伟德体育投注 Kit
BTRC BTRC Antibody BTRC Protein BTRC cDNA BTRC 伟德体育投注 Kit
CACYBP CACYBP Antibody CACYBP Protein CACYBP cDNA CACYBP 伟德体育投注 Kit
CAMK2A CAMK2A Antibody CAMK2A Protein CAMK2A cDNA CAMK2A 伟德体育投注 Kit
CAMK2B CAMK2B Antibody CAMK2B Protein CAMK2B cDNA CAMK2B 伟德体育投注 Kit
CAMK2D CAMK2D Antibody CAMK2D Protein CAMK2D cDNA CAMK2D 伟德体育投注 Kit
CAMK2G CAMK2G Antibody CAMK2G Protein CAMK2G cDNA CAMK2G 伟德体育投注 Kit
CCND1 CCND1 Antibody CCND1 Protein CCND1 cDNA CCND1 伟德体育投注 Kit
CCND2 CCND2 Antibody CCND2 Protein CCND2 cDNA CCND2 伟德体育投注 Kit
CCND3 CCND3 Antibody CCND3 Protein CCND3 cDNA CCND3 伟德体育投注 Kit
CER1 CER1 Antibody CER1 Protein CER1 cDNA CER1 伟德体育投注 Kit
CHD8 CHD8 Antibody CHD8 Protein CHD8 cDNA CHD8 伟德体育投注 Kit
CREBBP CREBBP Antibody CREBBP Protein CREBBP cDNA CREBBP 伟德体育投注 Kit
CSNK1A1 CSNK1A1 Antibody CSNK1A1 Protein CSNK1A1 cDNA CSNK1A1 伟德体育投注 Kit
CSNK1A1L CSNK1A1L Antibody CSNK1A1L Protein CSNK1A1L cDNA CSNK1A1L 伟德体育投注 Kit
CSNK2A1 CSNK2A1 Antibody CSNK2A1 Protein CSNK2A1 cDNA CSNK2A1 伟德体育投注 Kit